Description / Application
Memantine hydrochloride is a hydrochloride obtained by reaction of memantine with one equivalent of hydrochloric acid. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. It has a role as an antidepressant, an antiparkinson drug, a dopaminergic agent, a NMDA receptor antagonist and a neuroprotective agent. It contains a memantinium(1+).
Identities
| Alternative Name | 3,5-Dimethyl-1-adamantanamine hydrochloride; 3,5-Dimethylamantadine hydrochloride; 1,3-Dimethyl-5-aminoadamantane hydrochloride; 1-Amino-3,5-dimethyladamantane hydrochloride; Memantine Hydrochloride |
|---|---|
| Molecular Formula | C12H22ClN |
| Molecular Weight | 215.76 |
| MFCD | MFCD00214336 |
Safety
| Pictograms |
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|---|---|
| Signal Word | Warning |
| Hazard Statements | H315;H319;H335 |
| Precautionary Statements | P261;P264;P271;P280;P302+P352;P304+P340;P305+P351+P338;P312;P321;P332+P313;P337+P313;P362;P403+P233;P405;P501 |